NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) Peptide
NKIRAS1
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN937066
Aperçu rapide pour NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) Peptide (ABIN937066)
Antigène
NKIRAS1
(NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- CETMEDVYMA SVETDRGVKE QLHLYDTRGL QEGVELPKHY FSFADGFVLV
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of NKIRAS1 antibody,
Alternative Names: NKIRAS1 control peptide, NKIRAS1 antibody Blocking Peptide, Anti-NKIRAS1 Blocking Peptide, Nfkb Inhibitor Interacting Ras-Like 1 Blocking Peptide, KBRAS1 Blocking Peptide, kappaB-Ras1 Blocking Peptide, NKIRAS1, NKIRAS-1, NKIRAS 1, NKIRAS-1 Blocking Peptide, NKIRAS 1 Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
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Sujet
- NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
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Poids moléculaire
- 22 kDa
Antigène
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